Treatment
The choice of drug depends on the type of clinical presentation and the site of drug action (in the intestinal wall versus inside the intestine itself). The objective is to cure invasive disease at both intestinal and extraintestinal sites. More over the objective is to eliminate the passage of cysts from intestinal lumen.
These drugs include metronidazole (Flagyl) and tinidazole (Tindamax, Fasigyn). Metronidazole usually is given for 10 days, either by mouth or directly into the veins (intravenously). To kill amoebas and cysts confined to the intestine, three drugs called luminal drugs are available: iodoquinol (Diquinol and others), paromomycin (Humatin) and diloxanide furoate (Furamide). One of these drugs is used along with metronidazole when gastrointestinal symptoms are present. In people who pass amoebas in their stools without having symptoms of amebiasis, the luminal drugs alone can clear the amoebas from the bowel.
For the non-pathogenic parasite such as Entamoeba hartmanni and Iodamoeba butschlii there is no treatment acquired but prevention to avoid the infection must be practice.
These drugs include metronidazole (Flagyl) and tinidazole (Tindamax, Fasigyn). Metronidazole usually is given for 10 days, either by mouth or directly into the veins (intravenously). To kill amoebas and cysts confined to the intestine, three drugs called luminal drugs are available: iodoquinol (Diquinol and others), paromomycin (Humatin) and diloxanide furoate (Furamide). One of these drugs is used along with metronidazole when gastrointestinal symptoms are present. In people who pass amoebas in their stools without having symptoms of amebiasis, the luminal drugs alone can clear the amoebas from the bowel.
For the non-pathogenic parasite such as Entamoeba hartmanni and Iodamoeba butschlii there is no treatment acquired but prevention to avoid the infection must be practice.
Prevention
- Integrated and community based efforts through health education and promotion.
- Improve environmental sanitation.
- Provide for:
- Sanitary disposal of human feces.
- Safe drinking water – boiled or filtered.
- Safe food – thorough washing of raw fruits and vegetables
- Monitor food handlers.
- Wash hand after use the toilet.
- Vaccines (animal models)-mucosal immune response recombinant amebic antigen more advantageous thaninactivated/attenuated ameba: serine rich E. histolyticaprotein (SREHR) adherence lectins (Gal/GalNac lectin) 29kDa cysteine rich amebic antigen.
- Improve environmental sanitation.
- Provide for:
- Sanitary disposal of human feces.
- Safe drinking water – boiled or filtered.
- Safe food – thorough washing of raw fruits and vegetables
- Monitor food handlers.
- Wash hand after use the toilet.
- Vaccines (animal models)-mucosal immune response recombinant amebic antigen more advantageous thaninactivated/attenuated ameba: serine rich E. histolyticaprotein (SREHR) adherence lectins (Gal/GalNac lectin) 29kDa cysteine rich amebic antigen.